When I damaged my left hand a while back (I burned myself), I found that I couldn't edit easily. Emacs keystrokes were so hard-wired in muscle memory I'd forgotten what I was typing. As the fingers to do it were unavailable, I had to think so hard to recall the keystrokes that I ended up forgetting what was trying to do. I ended up falling back on heavy mouse use.
Mmm. Yes, I'm also having some trouble with hot keys that I hit almost unconsciously. I think in general bucky-combinations – ctrl-alt-thingy and the like – are demanding in terms of needing several LH fingers at once, and therefore more of a problem...