Hmm, yes. Interestingly, it still kind of holds true even if you take out the physical part...

Sorry, what holds true? That the human mind (rather than the physical brain) is a badly designed pile of junk, or something related to my second paragraph, or what?

I didn't think it through, but I think I meant, that there's no particular reason that if one thing upsets you, you should thereafter feel shit about everything else as well, but there's a definite tendency to do so I'd be tempted to design away?